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KMID : 1123920090230030608
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Korean Journal of Oriental Physiology and Pathology
2009 Volume.23 No. 3 p.608 ~ p.612
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Effect of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium on Hydrogen Peroxide Production of Macrophage Treated with Toxicants
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Park Wan-Su
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Abstract
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The effect of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium Water extract (AFS) on hydrogen peroxide production within mouse macrophage Raw 264.7 Cells treated with EtOH, gallic acid, Nicotine, Acetaminophen, and Acetaldehyde was investigated through this study. AFS (0-400 ug/mL) was simultaneously treated with EtOH, gallic acid, Nicotine, Acetaminophen, and Acetaldehyde. And the intracellular productions of hydrogen peroxide were measured by dihydrorhodamine 123 (DHR) assay. AFS restorated the intracellular productions of hydrogen peroxide reduced by EtOH, gallic acid, Nicotine, Acetaminophen within Raw 264.7 Cells. AFS could be supposed to have the immunological activity concerned with macrophage’s oxidative burst.
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KEYWORD
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macrophage, sacchromyces cerevisiae, artemisiae argi folium, fermentation, hydrogen peroxide
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